SCHEMBL2580708

SCHEMBL2580708

C=CC(=O)Oc1ccc(Cc2ccc(OC(=O)C=C)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.68
ELANE P08246 1/20 0.53
KMT2A Q03164 4/20 0.44
SRD5A2 P31213 1/20 0.42
PDE6D O43924 1/20 0.42
SAE1 Q9UBE0 1/20 0.41
UBA2 Q9UBT2 1/20 0.41
STS P08842 1/20 0.39
PPARG P37231 3/20 0.39
PPARA Q07869 3/20 0.39
THRA P10827 1/20 0.37
PTPN1 P18031 1/20 0.37
POLB P06746 1/20 0.36
LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9406873 0.93 THRB (0.60) THRBELANEKMT2ASRD5A2PDE6D
SCHEMBL2432065 0.93 THRB (0.60) THRBELANESRD5A2PDE6DPPARG
SCHEMBL7212815 0.88 THRB (0.90) THRBELANEKMT2APPARGPPARA
SCHEMBL99981 0.88 THRB (0.68) THRBELANEKMT2APDE6DPPARG
SCHEMBL17791334 0.88 THRB (0.79) THRBELANEPDE6DPPARGPPARA
SCHEMBL2587522 0.87 THRB (0.64) THRBELANEKMT2APDE6DTHRA
SCHEMBL740668 0.87 THRB (0.54) THRBELANEKMT2ASRD5A2PDE6D
SCHEMBL4595847 0.84 THRB (0.74) THRBELANEKMT2APPARGPPARA
SCHEMBL13888390 0.84 THRB (0.64) THRBELANEPDE6D
SCHEMBL242424 0.84 THRB (0.78) THRBKMT2APDE6DPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023238828-A1 CURABLE COMPOSITION 株式会社ダイセル 2023-12-14 WO disclosed
EP-3159737-B1 LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT NISSAN CHEMICAL CORP (JP) 2021-05-26 EP disclosed
EP-3248060-B1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2020-09-02 EP disclosed
US-10647816-B2 Liquid crystal display device NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-05-12 US disclosed
US-10386681-B2 Liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-08-20 US disclosed
EP-3200022-B1 LIQUID CRYSTAL DISPLAY DEVICE NISSAN CHEMICAL CORP (JP) 2019-06-26 EP disclosed
US-10241359-B2 Liquid crystal display device NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-03-26 US disclosed
WO-2018113786-A1 CROSS-LINKABLE POLYMER BASED ON DIELS-ALDER REACTION AND USE THEREOF IN ORGANIC ELECTRONIC DEVICE 广州华睿光电材料有限公司 2018-06-28 WO disclosed
US-20170343840-A1 LIQUID CRYSTAL DISPLAY DEVICE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-30 US disclosed
EP-3217212-A1 LIQUID CRYSTAL DISPLAY ELEMENT Nissan Chemical Industries, Ltd. (JP) 2017-09-13 EP disclosed
US-6458908-B1 A PROCESS FOR PREPARING A SULFUR-CONTAINING UNSATURATED CARBOXYLATE COMPOUND AS CLAIMED IN CLAIM 1 COMPRISING REACTING A SULFUR-CONTAINING DERIVATIVE FOR OPTICAL POLYMERS MITSUI CHEMICALS, INC. (JP) 2002-10-01 US disclosed
US-20020080320-A1 Liquid crystal display device PIXEL DISPLAY LLC 2002-06-27 US disclosed
US-20020061995-A1 Acrylic ester compound and usage thereof MITSUI CHEMICALS, INC. (JP) 2002-05-23 US disclosed
EP-1193264-A1 Acrylic ester compound and usage thereof Mitsui Chemicals, Inc. (JP) 2002-04-03 EP disclosed
US-6256082-B1 Liquid crystal display with a liquid crystal orientation controlling electrode and processes for manufacturing and driving thereof NEC CORPORATION (JP) 2001-07-03 US disclosed
US-6177976-B1 Liquid crystal display NEC CORPORATION (JP) 2001-01-23 US disclosed
EP-1057808-A2 Sulfur-containing unsaturated carboxylate compound and its use Mitsui Chemicals, Inc. (JP) 2000-12-06 EP disclosed
US-6115093-A Liquid crystal display device having at least two micro areas of liquid crystal layer capable of being built up from a center of each pixel NEC CORPORATION (JP) 2000-09-05 US disclosed
US-5963290-A Liquid crystal display NEC CORPORATION (JP) 1999-10-05 US disclosed
EP-0805373-A2 Liquid crystal display NEC CORPORATION (JP) 1997-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061995-A1 Acrylic ester compound and usage thereof ASS1, HAT1, EIF2B1 THRB 3115/4885ELANE 538/4885KMT2A 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.