Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24835050 | 0.93 | AKT1 (0.49) | AKT1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL25975485 | 0.92 | AKT1 (0.50) | AKT1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL25967838 | 0.92 | AKT1 (0.50) | AKT1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL25979696 | 0.91 | AKT1 (0.50) | AKT1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL25967517 | 0.91 | AKT1 (0.49) | AKT1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL22519634 | 0.91 | AKT1 (0.49) | AKT1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL23630027 | 0.91 | AKT1 (0.48) | AKT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23630030 | 0.91 | AKT1 (0.48) | AKT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25873361 | 0.91 | AKT1 (0.48) | AKT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25984298 | 0.90 | AKT1 (0.47) | AKT1FAAHHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795225-B2 | Therapeutic binding molecules | MEDIMMUNE LIMITED (GB) | 2023-10-24 | — | — | US | disclosed |
| US-20230295293-A1 | BINDING MOLECULES AGAINST FRa | ASTRAZENECA AB (SE) | 2023-09-21 | — | — | US | disclosed |
| US-20220098308-A1 | THERAPEUTIC BINDING MOLECULES | MEDIMMUNE LIMITED (GB) | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795225-B2 | Therapeutic binding molecules | EPCAM, IGSF11, FCGR3B | AKT1 4206/4885FAAH 4661/4885HDAC3 2330/4885 |
| US-20230295293-A1 | BINDING MOLECULES AGAINST FRa | FRG1, FRS2, TFRC | AKT1 3030/4885FAAH 3256/4885HDAC3 1834/4885 |
| US-20220098308-A1 | THERAPEUTIC BINDING MOLECULES | EPCAM, IGSF11, FCGR3B | AKT1 4206/4885FAAH 4661/4885HDAC3 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.