SCHEMBL24322309

SCHEMBL24322309

N#Cc1cc(-c2cncc(-c3ccccc3)c2)ccc1F

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 18/20 0.78
CYP11B2 P19099 18/20 0.78
FLT3 P36888 1/20 0.57
ALDH1A1 P00352 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1514536 0.88 FLT3 (0.59) CYP11B1CYP11B2FLT3ALDH1A1NPSR1
SCHEMBL20460028 0.88 CYP11B2 (1.00) CYP11B1CYP11B2
SCHEMBL20938090 0.82 CYP11B1 (0.54) CYP11B1CYP11B2FLT3ALDH1A1NPSR1
SCHEMBL2653236 0.80 GABRG2 (0.63) CYP11B1CYP11B2FLT3
SCHEMBL26073212 0.79 ABCG2 (0.55) CYP11B1CYP11B2FLT3ALDH1A1NPSR1
SCHEMBL23519333 0.79 ABCG2 (0.55) CYP11B1CYP11B2FLT3ALDH1A1NPSR1
SCHEMBL24322305 0.79 FLT3 (0.52) CYP11B1CYP11B2FLT3ALDH1A1NPSR1
SCHEMBL2924723 0.78 PIK3CD (0.50) CYP11B1CYP11B2FLT3
SCHEMBL24322662 0.78 ABCG2 (0.56) CYP11B1CYP11B2FLT3ALDH1A1NPSR1
SCHEMBL20114641 0.78 ABCG2 (0.56) CYP11B1CYP11B2FLT3ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220077402-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC COMPOUND LG DISPLAY CO., LTD. (KR) 2022-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220077402-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC COMPOUND OCIAD1, OCIAD2, NLRP3 CYP11B1 1105/4885CYP11B2 887/4885FLT3 3901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.