Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.66 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 4/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328840 | 0.86 | NPC1 (0.55) | BCAT2AOC3NPC1RAB9ATAAR1 | |
| SCHEMBL2328836 | 0.86 | NPC1 (0.55) | BCAT2AOC3NPC1RAB9ATAAR1 | |
| SCHEMBL4530460 | 0.85 | NPC1 (0.61) | AOC3NPC1RAB9ATAAR1MEN1 | |
| SCHEMBL8384291 | 0.83 | MTNR1A (0.60) | AOC3NPC1RAB9ATAAR1TP53 | |
| SCHEMBL2091303 | 0.83 | MTNR1A (0.60) | AOC3NPC1RAB9ATAAR1TP53 | |
| Hydrochloric Acid SCHEMBL4323386 | 0.83 | TAAR1 (0.60) | AOC3NPC1RAB9ATAAR1MEN1 | |
| SCHEMBL8384245 | 0.83 | MTNR1A (0.60) | AOC3NPC1RAB9ATAAR1TP53 | |
| SCHEMBL3903374 | 0.82 | BCAT2 (0.72) | BCAT2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12862954 | 0.81 | NPC1 (0.58) | AOC3NPC1RAB9ATAAR1KMT2A | |
| SCHEMBL17198959 | 0.81 | AOC3 (0.58) | BCAT2AOC3NPC1RAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | claimed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | claimed |
| WO-2011107443-A1 | USE OF PROPINEB FOR PHYSIOLOGICAL CURATIVE TREATMENT UNDER ZINC DEFICIENCY | BAYER CROPSCIENCE AG (DE) | 2011-09-09 | — | — | WO | disclosed |
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | disclosed |