Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 4/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.50 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4323386 | 0.98 | TAAR1 (0.60) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL23214150 | 0.89 | GRIA4 (0.58) | NPC1RAB9ATAAR1AOC3SMN1; SMN2 | |
| SCHEMBL2091303 | 0.86 | MTNR1A (0.60) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL8384291 | 0.86 | MTNR1A (0.60) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL8384245 | 0.86 | MTNR1A (0.60) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL8499532 | 0.85 | NPC1 (0.58) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL7909475 | 0.85 | NPC1 (0.58) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL2432247 | 0.85 | BCAT2 (0.66) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL12862954 | 0.85 | NPC1 (0.58) | NPC1RAB9ATAAR1AOC3TDP1 | |
| SCHEMBL7897225 | 0.85 | NPC1 (0.58) | NPC1RAB9ATAAR1AOC3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346411-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022253645-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-08 | — | — | WO | disclosed |
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
| EP-1937656-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS BETA 2 ADRENOCEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007027134-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ADRB2, ADRB1, ADRA2C | NPC1 3204/4885RAB9A 3463/4885TAAR1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.