Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033981 | 0.78 | BIRC2 (0.49) | BIRC2ALDH1A1LMNAMEN1POLB | |
| SCHEMBL25224263 | 0.78 | BIRC2 (0.49) | BIRC2ALDH1A1LMNAMEN1POLB | |
| SCHEMBL7498965 | 0.76 | CHRNB2 (0.42) | BIRC2CPN1CPB2SMYD3 | |
| SCHEMBL6290056 | 0.75 | ALDH1A1 (0.69) | ALDH1A1LMNAMEN1POLBMAPT | |
| SCHEMBL28923130 | 0.73 | BIRC2 (0.56) | BIRC2ALDH1A1LMNAMEN1POLB | |
| SCHEMBL22828732 | 0.73 | BIRC2 (0.56) | BIRC2ALDH1A1LMNAMEN1POLB | |
| SCHEMBL16509278 | 0.73 | BIRC2 (0.56) | BIRC2ALDH1A1LMNAMEN1POLB | |
| SCHEMBL28621816 | 0.73 | BIRC2 (0.51) | BIRC2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14307630 | 0.72 | DPP4 (0.42) | BIRC2DPP4PREPFAPDPP8 | |
| SCHEMBL10305143 | 0.71 | ALDH1A1 (0.53) | ALDH1A1LMNAMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | BIRC2 362/4885ALDH1A1 4556/4885LMNA 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.