Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 4/20 | 0.64 |
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | DRD3 | P35462 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878421 | 1.00 | L3MBTL1 (0.77) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| Dimethylamine SCHEMBL7279750 | 0.94 | L3MBTL1 (0.69) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL4577971 | 0.89 | L3MBTL1 (0.97) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL11240406 | 0.89 | L3MBTL1 (0.97) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL3970369 | 0.89 | L3MBTL1 (0.97) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL25010831 | 0.86 | KDM4E (1.00) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL25010832 | 0.86 | KDM4E (1.00) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL11537591 | 0.86 | KDM4E (1.00) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL12402885 | 0.85 | ATM (0.61) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL12402888 | 0.85 | ATM (0.61) | L3MBTL1KDM4ETSHRCYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | L3MBTL1 2569/4885KDM4E 4426/4885TSHR 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.