Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878421 | 0.94 | L3MBTL1 (0.77) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL24322808 | 0.94 | L3MBTL1 (0.77) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL4577971 | 0.84 | L3MBTL1 (0.97) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL11240406 | 0.84 | L3MBTL1 (0.97) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL3970369 | 0.84 | L3MBTL1 (0.97) | L3MBTL1KDM4ETSHRCYP2D6HIF1A | |
| SCHEMBL4864531 | 0.83 | KDM4E (0.74) | L3MBTL1KDM4ETSHRCYP2D6MEN1 | |
| SCHEMBL6754439 | 0.83 | USP2 (0.81) | L3MBTL1KDM4ETSHRCYP2D6MEN1 | |
| SCHEMBL4866196 | 0.82 | TP53 (0.73) | L3MBTL1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL24322624 | 0.82 | L3MBTL1 (0.72) | L3MBTL1TSHRMEN1KMT2APOLB | |
| SCHEMBL20444278 | 0.81 | KMT2A (0.76) | L3MBTL1KDM4ETSHRCYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |