SCHEMBL24323532

SCHEMBL24323532

CCNCC(=O)N1CCCC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
DPP4 P27487 5/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ATM Q13315 1/20 0.46
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
RAB9A P51151 1/20 0.41
CYP2D6 P10635 2/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24818614 0.96 DPP4 (0.47) L3MBTL1DPP4KMT2AMEN1TDP1
SCHEMBL10487028 0.86 ATM (0.54) L3MBTL1DPP4KMT2AMEN1TDP1
SCHEMBL2646670 0.83 DPP4 (0.50) L3MBTL1DPP4KMT2AMEN1TDP1
SCHEMBL13422266 0.83 HTR1A (0.46) L3MBTL1DPP4KMT2ATDP1ALDH1A1
SCHEMBL24322565 0.82 HTT (0.56) L3MBTL1ALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL3312154 0.82 DPP4 (0.41) L3MBTL1DPP4KMT2AMEN1TDP1
SCHEMBL18330367 0.80 ALDH1A1 (0.56) L3MBTL1DPP4KMT2AMEN1ALDH1A1
SCHEMBL20095024 0.79 DPP4 (0.50) L3MBTL1DPP4KMT2AMEN1TDP1
SCHEMBL8299375 0.79 L3MBTL1 (0.49) L3MBTL1DPP4KMT2ATDP1ATM
SCHEMBL22349073 0.79 L3MBTL1 (0.55) L3MBTL1KMT2AMEN1TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof Psomagen Inc. (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof HTRA1, GIPR, HPN L3MBTL1 2569/4885DPP4 532/4885KMT2A 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.