Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768706 | 0.85 | SLC1A1 (0.50) | CYP2D6CYP2C19HPGDSLC1A2SLC1A1 | |
| SCHEMBL14381159 | 0.85 | CYP2D6 (0.42) | CYP2D6CYP2C19HPGDALDH1A1DPP4 | |
| SCHEMBL1768701 | 0.85 | SLC1A1 (0.50) | CYP2D6CYP2C19HPGDSLC1A2SLC1A1 | |
| SCHEMBL14612078 | 0.80 | CYP2D6 (0.41) | CYP2D6CYP2C19HPGDDPP7SLC1A2 | |
| SCHEMBL9349283 | 0.80 | CYP2D6 (0.52) | CYP2D6CYP2C19HPGDALDH1A1EPHX2 | |
| SCHEMBL13789959 | 0.78 | SLC7A5 (0.54) | CYP2D6CYP2C19HPGDSLC1A2SLC1A1 | |
| SCHEMBL5224064 | 0.78 | DPP7 (0.66) | CYP2D6CYP2C19DPP4DPP8DPP9 | |
| SCHEMBL25023424 | 0.77 | NOD1 (0.46) | ALDH1A1DPP4DPP8DPP9DPP7 | |
| SCHEMBL25015353 | 0.76 | DPP7 (0.64) | DPP4DPP8DPP9DPP7SLC1A2 | |
| SCHEMBL22369853 | 0.76 | GNAI3 (0.59) | DPP4DPP8DPP9DPP7MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | CYP2D6 4712/4885CYP2C19 4010/4885HPGD 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.