Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770931 | 0.77 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2ALDH1A1CASP1CASP7 | |
| SCHEMBL795400 | 0.77 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2ALDH1A1CASP1CASP7 | |
| SCHEMBL7802853 | 0.74 | MAPK1 (0.53) | RAB9ASMN1; SMN2ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7806227 | 0.74 | MAPK1 (0.53) | RAB9ASMN1; SMN2ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7796006 | 0.73 | HTT (0.49) | RAB9ASMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7804745 | 0.73 | HTT (0.49) | RAB9ASMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL770889 | 0.72 | RAB9A (0.45) | RAB9ASMN1; SMN2ALDH1A1CASP1CASP7 | |
| SCHEMBL771541 | 0.72 | RAB9A (0.45) | RAB9ASMN1; SMN2ALDH1A1CASP1CASP7 | |
| SCHEMBL17532412 | 0.71 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL14084962 | 0.71 | MAPT (0.48) | SMN1; SMN2ALDH1A1DDB1CRBNGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | RAB9A 435/4885SMN1; SMN2 4226/4885ALDH1A1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.