Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437368 | 0.73 | SIRT1 (0.31) | — | |
| SCHEMBL2427124 | 0.70 | HSD17B3 (0.30) | MEN1KMT2A | |
| SCHEMBL2434332 | 0.70 | — | — | |
| SCHEMBL5473668 | 0.70 | BRPF1 (0.31) | MEN1KMT2A | |
| SCHEMBL2435594 | 0.66 | IDO1 (0.35) | MEN1KMT2A | |
| SCHEMBL2431727 | 0.65 | PDK1 (0.32) | — | |
| SCHEMBL5473904 | 0.65 | BRPF1 (0.30) | — | |
| SCHEMBL2435591 | 0.64 | KDM4E (0.32) | — | |
| SCHEMBL2427131 | 0.64 | — | — | |
| SCHEMBL5483296 | 0.64 | HSD17B3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212946-A1 | Quinolone Neuropeptide S Receptor Antagonists | MERCK SHARP & DOHME LLC | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212946-A1 | Quinolone Neuropeptide S Receptor Antagonists | NPSR1, NPY1R, NPY2R | MEN1 1784/4885KMT2A 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.