Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19582597 | 0.92 | MAPT (0.42) | MAPTSIGMAR1CYP2A13KDM4EALDH1A1 | |
| SCHEMBL1556809 | 0.83 | CYP2D6 (0.50) | SIGMAR1ALDH1A1CYP2D6OPRM1 | |
| SCHEMBL4875396 | 0.77 | CYP2D6 (0.55) | SIGMAR1ALDH1A1CYP2D6SMN1; SMN2CXCR4 | |
| SCHEMBL19603306 | 0.76 | CYP2D6 (0.41) | SIGMAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6284645 | 0.75 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1HTTCYP2D6SMN1; SMN2 | |
| SCHEMBL21538553 | 0.74 | MEN1 (0.50) | SIGMAR1ALDH1A1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL323276 | 0.73 | CYP2D6 (0.52) | SIGMAR1ALDH1A1CYP2D6SMN1; SMN2CXCR4 | |
| SCHEMBL6012435 | 0.73 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1CYP2D6CXCR4SLC6A2 | |
| SCHEMBL18917920 | 0.72 | ALDH1A1 (0.56) | MAPTSIGMAR1CYP2A13KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL322816 | 0.71 | CYP2D6 (0.51) | SIGMAR1ALDH1A1CYP2D6SMN1; SMN2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | MAPT 4494/4885SIGMAR1 3622/4885CYP2A13 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.