Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322881 | 0.93 | ALOX15 (0.31) | MMP1MMP2ALOX15CA12CA1 | |
| SCHEMBL18769513 | 0.89 | — | — | |
| SCHEMBL28012460 | 0.75 | TSHR (0.42) | MMP1MMP2ALOX15TSHRCA12 | |
| SCHEMBL23005668 | 0.75 | CYP3A4 (0.32) | ALOX15TSHRCYP3A4L3MBTL1 | |
| SCHEMBL28200676 | 0.75 | LAP3 (0.36) | ALOX15TSHR | |
| SCHEMBL3822982 | 0.74 | TSHR (0.33) | ALOX15TSHRCYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL1921577 | 0.74 | TSHR (0.33) | TSHRCYP3A4L3MBTL1ACHE | |
| SCHEMBL3824231 | 0.72 | TSHR (0.32) | MMP1MMP2TSHRMMP3 | |
| SCHEMBL18769166 | 0.70 | SMPD1 (0.45) | MMP1MMP2CA12CA1CA2 | |
| SCHEMBL28360605 | 0.70 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362461-B1 | MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE | MODERNATX INC (US) | 2022-03-16 | — | — | EP | disclosed |