Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
| ▸ | HAT1 | O14929 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92350 | 0.79 | NPC1 (0.57) | NPC1MEN1KMT2ACFTRALDH1A1 | |
| SCHEMBL2430369 | 0.78 | NPC1 (0.50) | NPC1MEN1KMT2ACFTRNHERF1 | |
| SCHEMBL27596527 | 0.77 | NPC1 (0.52) | NPC1MEN1KMT2ACFTRALDH1A1 | |
| SCHEMBL8258117 | 0.76 | NPC1 (0.65) | NPC1MEN1KMT2ACFTRALDH1A1 | |
| SCHEMBL2432899 | 0.75 | RAB9A (0.43) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14592280 | 0.75 | PKM (0.51) | NPC1MEN1KMT2ACFTRMAPT | |
| SCHEMBL27578666 | 0.74 | NPC1 (0.58) | NPC1MEN1KMT2ACFTRMAPT | |
| SCHEMBL1308599 | 0.72 | CDK2 (0.61) | NPC1MEN1KMT2ACFTRMAPT | |
| SCHEMBL27075304 | 0.70 | NPC1 (0.68) | NPC1MEN1KMT2ACFTRALDH1A1 | |
| SCHEMBL92386 | 0.69 | NPC1 (0.64) | NPC1MEN1KMT2ACFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |