Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352114 | 0.93 | SLC22A2 (0.34) | SLC22A2SLC22A1SLC22A3SLC6A4MAPT | |
| SCHEMBL3352109 | 0.90 | — | — | |
| SCHEMBL9008149 | 0.86 | TP53 (0.34) | TP53KDM4ELIPGADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL2259177 | 0.77 | ACP3 (0.34) | — | |
| SCHEMBL17996991 | 0.73 | HTR2A (0.41) | SLC22A2SLC22A1SLC22A3SLC6A4MEN1 | |
| SCHEMBL142479 | 0.71 | ADRA2B (0.44) | TP53KDM4ELIPGADRA2AADRA2B | |
| SCHEMBL29488434 | 0.71 | ADRA2B (0.44) | TP53KDM4ELIPGADRA2AADRA2B | |
| Benzene SCHEMBL11786397 | 0.69 | KDM4E (0.44) | TP53KDM4ELIPGADRA2AADRA2B | |
| SCHEMBL9839840 | 0.69 | ADRA2B (0.43) | KDM4ELIPGADRA2AADRA2BADRA2C | |
| SCHEMBL19888150 | 0.69 | ACHE (0.44) | SLC22A2SLC22A1SLC22A3SLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366127-A1 | ELECTROCHROMIC OPTICAL ELEMENT HAVING AN APODIZED APERTURE | PPG Industries Ohio, Inc. (US) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010065713-A1 | ELECTROCHROMIC OPTICAL ELEMENT HAVING AN APODIZED APERTURE | PPG INDUSTRIES OHIO, INC. (US) | 2010-06-10 | — | — | WO | disclosed |