Benzene

Benzene

SCHEMBL11786397

CCCc1ccccc1CCC.c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
TP53 P04637 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
PPARG P37231 3/20 0.42
PPARA Q07869 3/20 0.42
PSIP1 O75475 1/20 0.42
LIPG Q9Y5X9 1/20 0.41
HTR2A P28223 1/20 0.41
HTR1A P08908 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
KCNN4 O15554 1/20 0.39
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL29092952 0.97 LIPG (0.45) KDM4EALDH1A1GAAHPGDTP53
SCHEMBL29488434 0.97 ADRA2B (0.44) KDM4EALDH1A1GAAHPGDTP53
SCHEMBL142479 0.97 ADRA2B (0.44) KDM4EALDH1A1GAAHPGDTP53
SCHEMBL9839840 0.94 ADRA2B (0.43) KDM4EALDH1A1GAAHPGDADRA2A
SCHEMBL31613870 0.88 GABRA1 (0.46) TP53ADRA2AADRA2BADRA2CPPARG
SCHEMBL9276351 0.88 LIPG (0.54) ADRA2AADRA2BADRA2CPPARGPPARA
SCHEMBL327380 0.88 GABRA1 (0.46) TP53ADRA2AADRA2BADRA2CPPARG
SCHEMBL5437047 0.88 HTR2A (0.43) KDM4EALDH1A1GAAHPGDADRA2A
SCHEMBL6546789 0.87 HTR1A (0.48) KDM4EALDH1A1HPGDTP53HTR2A
Phenol SCHEMBL28183999 0.87 CA12 (0.52) KDM4EALDH1A1TP53ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3975454-A GRAPHITE-ALKALI METAL SAGAMI CHEMICAL RESEARCH CENTER (JA) 1976-08-17 US disclosed