Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19577449 | 0.84 | ATF4 (0.47) | ATF4 | |
| SCHEMBL24323095 | 0.84 | ATF4 (0.47) | ATF4 | |
| SCHEMBL24323100 | 0.83 | ATF4 (0.43) | ATF4 | |
| SCHEMBL24324588 | 0.82 | ATF4 (0.46) | ATF4 | |
| SCHEMBL24324496 | 0.82 | ATF4 (0.47) | ATF4 | |
| SCHEMBL24322856 | 0.82 | ALDH1A1 (0.48) | ATF4 | |
| SCHEMBL24323038 | 0.81 | ATF4 (0.48) | ATF4 | |
| SCHEMBL24323279 | 0.81 | ATF4 (0.47) | ATF4 | |
| SCHEMBL24323398 | 0.81 | ATF4 (0.47) | ATF4 | |
| SCHEMBL24323037 | 0.80 | ATF4 (0.45) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452453-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2022-04-13 | — | — | EP | disclosed |