SCHEMBL2432485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2434369	0.99	HTR1A (0.40)	HTR1AHTR7MAPTTP53ALDH1A1
	SCHEMBL2432794	0.90	MAPT (0.39)	HTR1AHTR7MAPTTP53ALDH1A1
	SCHEMBL2430714	0.89	PRKDC (0.42)	HTR1AHTR7ALDH1A1SMN1; SMN2GAA
	SCHEMBL1136220	0.87	HTR1A (0.39)	HTR1AHTR7MAPTTP53ALDH1A1
	SCHEMBL2428888	0.80	HPGD (0.47)	ALDH1A1KDM4ESMN1; SMN2TDP1GAA
	SCHEMBL2435481	0.78	CYP19A1 (0.41)	ALDH1A1KDM4EKMT2ATDP1IDO1
	SCHEMBL1136064	0.78	KDM1A (0.42)	ALDH1A1KDM4ESMN1; SMN2TDP1GAA
	SCHEMBL2430093	0.77	IDO1 (0.40)	MAPTTP53ALDH1A1KDM4EKMT2A
	SCHEMBL2433379	0.75	PDE4D (0.38)	IDO1FLT3
	SCHEMBL2430728	0.74	IDO1 (0.38)	MAPTALDH1A1KDM4EKMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.