SCHEMBL2435481

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2434369	0.78	HTR1A (0.40)	IDO1ALDH1A1KDM4EKMT2ATDP1
	SCHEMBL2431857	0.78	IDO1 (0.34)	IDO1ALDH1A1KDM4EKMT2A
	SCHEMBL2432485	0.78	HTR1A (0.39)	IDO1ALDH1A1KDM4EKMT2ATDP1
	SCHEMBL2432794	0.77	MAPT (0.39)	IDO1ALDH1A1KDM4EKMT2A
	SCHEMBL2430714	0.76	PRKDC (0.42)	ALDH1A1MAPK1
	SCHEMBL2430093	0.75	IDO1 (0.40)	CYP19A1MAOAMAOBIDO1ALDH1A1
	SCHEMBL2430483	0.70	IDO1 (0.38)	CYP19A1MAOAMAOBIDO1ALDH1A1
	SCHEMBL16938500	0.70	MEN1 (0.44)	CYP19A1MAOAMAOBIDO1ALDH1A1
	SCHEMBL2427405	0.70	SIK1 (0.43)	MAOAMAOBIDO1ALDH1A1KMT2A
	SCHEMBL2432159	0.70	NPC1 (0.37)	IDO1ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.