SCHEMBL24326548

SCHEMBL24326548

c1ccc(-n2c3ccccc3c3c4cc5cccc(-c6ccc(-n7c8ccccc8c8ccccc87)cc6)c5cc4ccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
HDAC4 P56524 1/20 0.34
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
MAPK14 Q16539 1/20 0.33
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
PDE6D O43924 1/20 0.32
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24326579 0.94 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL24326862 0.94 L3MBTL1 (0.43) L3MBTL1KDM4EATMHDAC4JAK2
SCHEMBL24326542 0.94 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4JAK2
SCHEMBL24326578 0.93 L3MBTL1 (0.39) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL24326568 0.93 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4JAK2
SCHEMBL24326553 0.93 KDM4E (0.44) L3MBTL1KDM4EATMHDAC4JAK2
SCHEMBL24326898 0.91 L3MBTL1 (0.40) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL24326562 0.91 KDM4E (0.40) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL18566853 0.90 L3MBTL1 (0.34) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL18566844 0.89 L3MBTL1 (0.35) L3MBTL1KDM4EATMALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220123231-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, Display Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123231-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, Display Device, and Lighting Device SUN2, CRY2, NBAS L3MBTL1 721/4885KDM4E 2685/4885ATM 3208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.