Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24326270 | 0.91 | FFAR4 (0.32) | GAAALOX15FFAR4 | |
| SCHEMBL24325715 | 0.88 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL24326652 | 0.87 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL24325712 | 0.87 | — | — | |
| SCHEMBL24325812 | 0.82 | MAP4K1 (0.39) | — | |
| SCHEMBL24326123 | 0.79 | CYBB (0.33) | GAA | |
| SCHEMBL24325710 | 0.78 | HRH3 (0.31) | — | |
| SCHEMBL24326318 | 0.78 | DRD2 (0.44) | — | |
| SCHEMBL27012775 | 0.77 | PARP1 (0.32) | PARP1 | |
| SCHEMBL24325796 | 0.77 | FFAR4 (0.31) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076625-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |