Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22525461 | 0.86 | ANPEP (0.37) | ALDH1A1POLBDPP4ANPEPLMNA | |
| SCHEMBL21308302 | 0.85 | ALDH1A1 (0.46) | ALDH1A1POLBL3MBTL1DPP4LMNA | |
| SCHEMBL21308307 | 0.85 | ALDH1A1 (0.43) | ALDH1A1POLBL3MBTL1DPP4ANPEP | |
| SCHEMBL6261469 | 0.85 | ALDH1A1 (0.53) | ALDH1A1POLBL3MBTL1DPP4ANPEP | |
| SCHEMBL17884698 | 0.84 | ALDH1A1 (0.45) | ALDH1A1POLBL3MBTL1DPP4ANPEP | |
| SCHEMBL20046786 | 0.83 | ALDH1A1 (0.44) | ALDH1A1POLBL3MBTL1LMNAHTT | |
| SCHEMBL21136309 | 0.83 | ALDH1A1 (0.41) | ALDH1A1POLBL3MBTL1LMNAHTT | |
| SCHEMBL21308118 | 0.83 | TNF (0.44) | ALDH1A1POLBL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL21349847 | 0.82 | ALDH1A1 (0.60) | ALDH1A1POLBL3MBTL1LMNAKDM4E | |
| SCHEMBL6257151 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBL3MBTL1DPP4ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068933-A1 | COMPOUNDS AND METHODS OF TREATING DISEASES | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-07 | — | — | WO | disclosed |