Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24326991 | 0.92 | ALOX12 (0.42) | ALOX12MEN1KMT2AMAPTCNR2 | |
| SCHEMBL24326990 | 0.87 | MAPT (0.46) | ALOX12MEN1KMT2AMAPTCNR2 | |
| SCHEMBL26777795 | 0.83 | FNTA (0.35) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL24328583 | 0.81 | ALOX12 (0.43) | ALOX12MEN1KMT2AMAPTCNR2 | |
| SCHEMBL24327001 | 0.78 | KMT2A (0.63) | ALOX12MEN1KMT2AMAPTTSHR | |
| SCHEMBL14591313 | 0.77 | ALOX12 (0.47) | ALOX12MEN1KMT2AMAPTCNR2 | |
| SCHEMBL24327005 | 0.77 | ALOX12 (0.34) | ALOX12MEN1KMT2AMAPTCNR2 | |
| SCHEMBL3665951 | 0.74 | MEN1 (0.58) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL26777798 | 0.74 | L3MBTL1 (0.36) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL24328578 | 0.74 | ALOX12 (0.44) | ALOX12MEN1KMT2AMAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063106-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BEIGENE, LTD. (KY) | 2022-03-31 | — | — | WO | disclosed |