Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2694560 | 0.84 | MEN1 (0.69) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL29777994 | 0.80 | KMT2A (0.63) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL5617272 | 0.78 | HTR7 (0.56) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL14383294 | 0.78 | DRD3 (0.57) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL22566225 | 0.78 | MEN1 (0.73) | MEN1KMT2AALDH1A1TSHRPOLB | |
| Hydrochloric Acid SCHEMBL5617259 | 0.77 | DRD3 (0.56) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL28867076 | 0.76 | KMT2A (0.67) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL14498366 | 0.75 | L3MBTL1 (0.57) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL5617322 | 0.75 | DRD2 (0.57) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL24326985 | 0.74 | ALOX12 (0.40) | MEN1KMT2AALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781481-B2 | N-arylsulfonyl-2,3-dihydro-1H-indoles and the use thereof as CCR9 inhibitors | NOVARTIS AG (CH) | 2010-08-24 | — | — | US | disclosed |