SCHEMBL24327002

SCHEMBL24327002

CCN1/C(=C/C=C/c2sc3cc(NC(C)=O)ccc3[n+]2CC)Sc2cc(NC(C)=O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 2/20 0.66
▸ MEN1 O00255 6/20 0.58
▸ KMT2A Q03164 6/20 0.58
▸ HTT P42858 4/20 0.58
▸ BLM P54132 4/20 0.58
▸ APP P05067 6/20 0.58
▸ NPC1 O15118 4/20 0.58
▸ RAB9A P51151 4/20 0.58
▸ APAF1 O14727 2/20 0.58
▸ ITGB2 P05107 1/20 0.58
▸ ALPL P05186 1/20 0.58
▸ ITGAM P11215 1/20 0.58
▸ GFER P55789 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ ALDH1A1 P00352 2/20 0.54
▸ POLB P06746 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ THRB P10828 2/20 0.54
▸ PKM P14618 2/20 0.54
▸ RECQL P46063 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL26664786 0.99 PRMT1 (0.68) PRMT1MEN1KMT2AHTTBLM
Iodide SCHEMBL29556211 0.99 PRMT1 (0.68) PRMT1MEN1KMT2AHTTBLM
Iodide SCHEMBL26664736 0.85 MEN1 (0.62) PRMT1MEN1KMT2AHTTBLM
Iodide SCHEMBL29556328 0.85 MEN1 (0.62) PRMT1MEN1KMT2AHTTBLM
SCHEMBL26795012 0.82 NSD2 (0.57) PRMT1MEN1KMT2AHTTBLM
SCHEMBL27391249 0.81 PRMT1 (0.75) PRMT1MEN1KMT2AHTTBLM
SCHEMBL26794997 0.81 PRMT1 (0.74) PRMT1MEN1KMT2AHTTBLM
Iodide SCHEMBL29556031 0.80 PRMT1 (0.76) PRMT1MEN1KMT2AHTTBLM
Hydrochloric Acid SCHEMBL29556620 0.80 PRMT1 (0.73) PRMT1MEN1KMT2AHTTBLM
Hydrochloric Acid SCHEMBL26664761 0.80 PRMT1 (0.73) PRMT1MEN1KMT2AHTTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372310-A1 Flavi-Block: A Pan-Flavivirus Inhibitor BADEN-WÜRTTEMBERG STIFTUNG GMBH (DE) 2023-11-23 — — US disclosed
WO-2022078602-A1 FLAVI-BLOCK: A PAN-FLAVIVIRUS INHIBITOR BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372310-A1 Flavi-Block: A Pan-Flavivirus Inhibitor MAVS, EIF2AK2, BLVRB PRMT1 3292/4885MEN1 4451/4885KMT2A 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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