Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111720 | 0.78 | VHL (0.64) | ADH1BADH1CADH1AADH7VHL | |
| SCHEMBL13799002 | 0.76 | NPC1 (0.37) | NPC1RAB9AMAPTHPGDCASP3 | |
| SCHEMBL24440138 | 0.75 | NPC1 (0.40) | VHLALOX5NPC1RAB9AMAPT | |
| SCHEMBL20111748 | 0.74 | ADH1B (0.44) | ADH1BADH1CADH1AADH7VHL | |
| SCHEMBL24327094 | 0.74 | HRH3 (0.46) | ADRB2PDCD1CD274 | |
| SCHEMBL8763196 | 0.72 | ADH1B (0.76) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL31566 | 0.70 | ADH1B (0.61) | ADH1BADH1CADH1AADH7NPC1 | |
| SCHEMBL1691160 | 0.68 | ADH1B (0.76) | ADH1BADH1CADH1AADH7RAB9A | |
| SCHEMBL5451697 | 0.68 | ADH1B (0.76) | ADH1BADH1CADH1AADH7RAB9A | |
| SCHEMBL22157991 | 0.67 | NPC1 (0.49) | ALOX5NPC1RAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068933-A1 | COMPOUNDS AND METHODS OF TREATING DISEASES | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-07 | — | — | WO | disclosed |