Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.76 |
| ▸ | ADH1C | P00326 | 1/20 | 0.76 |
| ▸ | ADH1A | P07327 | 1/20 | 0.76 |
| ▸ | ADH7 | P40394 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691160 | 1.00 | ADH1B (0.76) | ADH1BADH1CADH1AADH7RAB9A | |
| SCHEMBL27354 | 0.87 | ADH1B (1.00) | ADH1BADH1CADH1AADH7MEN1 | |
| Hydrochloric Acid SCHEMBL3741186 | 0.85 | ADH1B (0.95) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL8763196 | 0.84 | ADH1B (0.76) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL8473492 | 0.82 | ADH1B (0.68) | ADH1BADH1CADH1AADH7FFAR1 | |
| SCHEMBL27666130 | 0.82 | ADH1B (0.55) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL5420664 | 0.80 | FFAR1 (0.48) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL5428912 | 0.80 | ADH1B (0.70) | ADH1BADH1CADH1AADH7RAB9A | |
| SCHEMBL13925680 | 0.79 | RAB9A (0.52) | ADH1BADH1CADH1AADH7RAB9A | |
| SCHEMBL3311315 | 0.79 | ADH1B (0.68) | ADH1BADH1CADH1AADH7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117848-A1 | METALLOPROTEIN INHIBITORS | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO | 2007-05-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117848-A1 | METALLOPROTEIN INHIBITORS | SOD1, ZFX, SOD3 | ADH1B 664/4885ADH1C 1861/4885ADH1A 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.