Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327347 | 0.81 | KDR (0.53) | CNR1CNR2FGFR3KDRFGFR1 | |
| SCHEMBL29498933 | 0.81 | KDR (0.53) | CNR1CNR2FGFR3KDRFGFR1 | |
| SCHEMBL24328703 | 0.79 | FGFR3 (0.51) | CNR1CNR2FGFR3KDRFGFR1 | |
| SCHEMBL24327370 | 0.79 | FGFR3 (0.51) | CNR1CNR2FGFR3KDRFGFR1 | |
| SCHEMBL29498949 | 0.76 | FGFR3 (0.56) | CNR1CNR2FGFR3KDRFGFR1 | |
| SCHEMBL24327350 | 0.76 | FGFR3 (0.56) | CNR1CNR2FGFR3KDRFGFR1 | |
| SCHEMBL24327827 | 0.74 | FGFR3 (0.53) | FGFR3KDRFGFR1FGFR2CSF1R | |
| SCHEMBL24328681 | 0.72 | FGFR3 (0.49) | CNR1CNR2FGFR3KDRFGFR1 | |
| SCHEMBL24328711 | 0.72 | CHEK1 (0.52) | CNR1CNR2FGFR3KDRMAPT | |
| SCHEMBL24328713 | 0.72 | CNR1 (0.52) | CNR1CNR2FGFR3KDRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |