Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17936372 | 0.85 | CYP3A4 (0.52) | FADS1CDC25BALDH1A1HPGDALOX15 | |
| SCHEMBL11220891 | 0.77 | MAPT (0.59) | CDC25BALDH1A1HPGDATMSTK10 | |
| SCHEMBL24327929 | 0.72 | MAPT (0.51) | CDC25BALDH1A1HPGDATMGAA | |
| SCHEMBL24327488 | 0.72 | DHODH (0.54) | FADS1CDC25BALDH1A1HPGDTSHR | |
| SCHEMBL12283415 | 0.71 | MAPT (0.61) | CDC25BALDH1A1HPGDATMSTK10 | |
| SCHEMBL24327533 | 0.70 | MAPT (0.44) | CDC25BALDH1A1HPGDATMGAA | |
| SCHEMBL15906860 | 0.69 | MAPT (0.58) | CDC25BALDH1A1HPGDATMGAA | |
| SCHEMBL24328015 | 0.69 | TOP2A (0.48) | CDC25BALDH1A1HPGDATMCA1 | |
| SCHEMBL18674138 | 0.69 | CDC25B (0.60) | FADS1CDC25BALDH1A1HPGDALOX15 | |
| SCHEMBL5615168 | 0.68 | CDC25B (0.59) | FADS1CDC25BALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |