Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12283415 | 0.87 | MAPT (0.61) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL15906860 | 0.84 | MAPT (0.58) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL11220891 | 0.83 | MAPT (0.59) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL24327929 | 0.81 | MAPT (0.51) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL24327528 | 0.80 | AKT1 (0.52) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL24327495 | 0.78 | NSD2 (0.49) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL24327488 | 0.75 | DHODH (0.54) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL24327533 | 0.73 | MAPT (0.44) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL197302 | 0.72 | GPR55 (0.55) | MAPTRAB9AHTTNPSR1NPC1 | |
| SCHEMBL29556949 | 0.72 | GPR55 (0.55) | MAPTRAB9AHTTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |