Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | STK10 | O94804 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327496 | 0.88 | ALDH1A1 (0.56) | DHODHHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL24327533 | 0.85 | MAPT (0.44) | DHODHHTTMAPTMEN1KMT2A | |
| SCHEMBL11220891 | 0.84 | MAPT (0.59) | DHODHHTTMAPTMEN1KMT2A | |
| SCHEMBL24327526 | 0.82 | DHODH (0.54) | DHODHP2RX1P2RX4P2RX7HTT | |
| SCHEMBL24327490 | 0.79 | PGR (0.53) | HTTMAPTMEN1KMT2ARAB9A | |
| SCHEMBL12283415 | 0.78 | MAPT (0.61) | DHODHHTTMAPTMEN1KMT2A | |
| SCHEMBL24327929 | 0.76 | MAPT (0.51) | DHODHHTTMAPTMEN1KMT2A | |
| SCHEMBL24328015 | 0.75 | TOP2A (0.48) | DHODHHTTMAPTMEN1KMT2A | |
| SCHEMBL15906860 | 0.75 | MAPT (0.58) | HTTMAPTMEN1KMT2ARAB9A | |
| SCHEMBL24327530 | 0.72 | FADS1 (0.42) | DHODHHTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |