Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | HTT | P42858 | 8/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | ATM | Q13315 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | CDC25A | P30304 | 3/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | CDC25C | P30307 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220891 | 0.91 | MAPT (0.59) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL12283415 | 0.84 | MAPT (0.61) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL15906860 | 0.81 | MAPT (0.58) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL24328015 | 0.81 | TOP2A (0.48) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL24327528 | 0.78 | AKT1 (0.52) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL24327488 | 0.76 | DHODH (0.54) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL24327533 | 0.74 | MAPT (0.44) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL24327490 | 0.73 | PGR (0.53) | MAPTRAB9AHTTNPSR1MAPK1 | |
| SCHEMBL24327928 | 0.73 | HKDC1 (0.49) | MAPTRAB9AHTTNPSR1KMT2A | |
| SCHEMBL24327530 | 0.72 | FADS1 (0.42) | MAPTRAB9AHTTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |