Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327883 | 0.85 | TEK (0.46) | KCNH2CDK2FGFR2FGFR3 | |
| SCHEMBL24327374 | 0.82 | KCNH2 (0.64) | KCNH2CCNE2CCNE1CDK2FGFR2 | |
| SCHEMBL29498950 | 0.82 | KCNH2 (0.64) | KCNH2CCNE2CCNE1CDK2FGFR2 | |
| SCHEMBL29498946 | 0.82 | KCNH2 (0.64) | KCNH2CCNE2CCNE1CDK2FGFR2 | |
| SCHEMBL24327260 | 0.80 | LRRK2 (0.45) | CDK2PIK3CAPI4KBFGFR2FGFR3 | |
| SCHEMBL24327354 | 0.79 | CNR1 (0.43) | KCNH2CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL24327941 | 0.79 | AXL (0.37) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL28724038 | 0.77 | TYK2 (0.39) | KCNH2CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL25404864 | 0.74 | MET (0.42) | KCNH2MAP4K4GRM2HSP90AA1NTRK1 | |
| SCHEMBL28724022 | 0.72 | CCNB2 (0.32) | CCNE2CCNE1CDK2CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |