Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724022 | 0.86 | CCNB2 (0.32) | AXLMAPK1CCNT1CCNB2CCNE2 | |
| SCHEMBL24327260 | 0.85 | LRRK2 (0.45) | AXLCHEK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24327354 | 0.84 | CNR1 (0.43) | AXLCHEK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24327883 | 0.84 | TEK (0.46) | AXLALOX5APCDK2TYK2 | |
| SCHEMBL29498947 | 0.80 | MAPK1 (0.51) | CHEK1ALOX5APFEN1MAPK1 | |
| SCHEMBL24327885 | 0.80 | MAPK1 (0.51) | CHEK1ALOX5APFEN1MAPK1 | |
| SCHEMBL24327872 | 0.79 | KCNH2 (0.46) | PIK3CAPI4KBCCNT1CCNB2CCNE2 | |
| SCHEMBL28724009 | 0.75 | PIK3CD (0.33) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL23430123 | 0.73 | GPR55 (0.49) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL28724038 | 0.72 | TYK2 (0.39) | CCNT1CCNB2CCNE2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |