Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724038 | 0.86 | TYK2 (0.39) | TEKEPHB4NPBWR1TLR8FGFR2 | |
| SCHEMBL24327260 | 0.85 | LRRK2 (0.45) | TEKEPHB4TLR8FGFR2FGFR3 | |
| SCHEMBL24327872 | 0.85 | KCNH2 (0.46) | FGFR2FGFR3KCNH2CDK2 | |
| SCHEMBL24327354 | 0.84 | CNR1 (0.43) | TLR8FGFR3KCNH2AXLKDR | |
| SCHEMBL24327941 | 0.84 | AXL (0.37) | AXLTYK2ALOX5APCDK2 | |
| SCHEMBL24327773 | 0.80 | KCNH2 (0.55) | TEKEPHB4NPBWR1FGFR2FGFR3 | |
| SCHEMBL24328691 | 0.74 | EPHB4 (0.46) | TEKEPHB4NPBWR1TLR8FGFR2 | |
| SCHEMBL29498914 | 0.74 | EPHB4 (0.46) | TEKEPHB4NPBWR1TLR8FGFR2 | |
| SCHEMBL28761425 | 0.74 | CHEK1 (0.45) | TEKEPHB4NPBWR1FGFR2FGFR3 | |
| SCHEMBL28724022 | 0.72 | CCNB2 (0.32) | FGFR2FGFR3AXLTYK2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |