Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2427296 | 0.90 | PIM1 (0.48) | PIM1PIM3DAPK3PLK1HASPIN | |
| SCHEMBL2433136 | 0.86 | PIM1 (0.41) | PIM1PIM3DAPK3PLK1HASPIN | |
| SCHEMBL2428650 | 0.72 | CASR (0.42) | PIM1PIM3MAPTALDH1A1KDM4E | |
| SCHEMBL12324341 | 0.71 | KDM4E (0.44) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14867342 | 0.70 | CASR (0.40) | PIM1PIM3MAPTALDH1A1KDM4E | |
| SCHEMBL12324331 | 0.70 | MAPT (0.44) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL14871602 | 0.70 | MAPT (0.44) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2429295 | 0.69 | MAPT (0.43) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2432112 | 0.69 | MAPT (0.49) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2427232 | 0.68 | LMNA (0.46) | PIM1PIM3MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542239-A1 | USE OF ISOQUINOLONES FOR PREPARING DRUGS, NOVEL ISOQUINOLONES AND METHOD FOR SYNTHESISING SAME | Université Joseph Fourier (FR) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107709-A1 | USE OF ISOQUINOLONES FOR PREPARING DRUGS, NOVEL ISOQUINOLONES AND METHOD FOR SYNTHESISING SAME | UNIVERSITE JOSEPH FOURIER (FR) | 2011-09-09 | — | — | WO | disclosed |