Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327489 | 0.71 | CDC25A (0.40) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL24327493 | 0.71 | CDC25A (0.42) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL24327529 | 0.71 | MAPT (0.47) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL24327930 | 0.70 | MAPT (0.46) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL13991788 | 0.69 | CYP19A1 (0.57) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL10351964 | 0.69 | CYP19A1 (0.57) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL24327927 | 0.69 | CDC25A (0.46) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL24327527 | 0.69 | CDC25A (0.46) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL24327487 | 0.69 | CDC25A (0.46) | NSD2HTTAPAF1MAPTNPC1 | |
| SCHEMBL10622173 | 0.68 | CYP19A1 (0.50) | NSD2HTTAPAF1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |