Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327527 | 1.00 | CDC25A (0.46) | CDC25ACDC25BMAPTLMNAHTT | |
| SCHEMBL24327487 | 1.00 | CDC25A (0.46) | CDC25ACDC25BMAPTLMNAHTT | |
| SCHEMBL24327930 | 0.98 | MAPT (0.46) | CDC25ACDC25BMAPTLMNAHTT | |
| SCHEMBL24327529 | 0.94 | MAPT (0.47) | CDC25ACDC25BMAPTLMNAHTT | |
| SCHEMBL1101039 | 0.81 | MAPT (0.46) | CDC25ACDC25BMAPTLMNAHTT | |
| SCHEMBL24327493 | 0.79 | CDC25A (0.42) | CDC25ACDC25BMAPTLMNAHTT | |
| SCHEMBL11371344 | 0.77 | CYP19A1 (0.71) | MAPTLMNAHTTGPR84CYP19A1 | |
| SCHEMBL7962344 | 0.76 | MAPT (0.70) | CDC25ACDC25BMAPTLMNAHTT | |
| SCHEMBL10899503 | 0.75 | ALDH1A1 (0.48) | MAPTGPR84CYP19A1MAPK1NPSR1 | |
| SCHEMBL10895412 | 0.75 | ALDH1A1 (0.48) | MAPTGPR84CYP19A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |