Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 6/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327940 | 0.78 | MEN1 (0.38) | CDC25AGPR55MAPTLMNAHTT | |
| SCHEMBL24327493 | 0.76 | CDC25A (0.42) | CDC25AGPR55MAPTLMNAHTT | |
| SCHEMBL24327529 | 0.76 | MAPT (0.47) | CDC25AGPR55MAPTLMNAHTT | |
| SCHEMBL24327930 | 0.75 | MAPT (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327527 | 0.73 | CDC25A (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327927 | 0.73 | CDC25A (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327487 | 0.73 | CDC25A (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327928 | 0.72 | HKDC1 (0.49) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327495 | 0.71 | NSD2 (0.49) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327948 | 0.71 | NSD2 (0.50) | CDC25AGPR55MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |