Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 4/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327529 | 0.81 | MAPT (0.47) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327930 | 0.80 | MAPT (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327527 | 0.79 | CDC25A (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327487 | 0.79 | CDC25A (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327927 | 0.79 | CDC25A (0.46) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327489 | 0.76 | CDC25A (0.40) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327928 | 0.74 | HKDC1 (0.49) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24327495 | 0.74 | NSD2 (0.49) | CDC25AMAPTLMNAHTTCDC25B | |
| SCHEMBL24328014 | 0.72 | OXTR (0.42) | CDC25AMAPTLMNAHTTGPR55 | |
| SCHEMBL197302 | 0.71 | GPR55 (0.55) | MAPTLMNAHTTCDC25BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |