Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 5/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328261 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL7854157 | 0.79 | ADRA2A (0.36) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL2835873 | 0.77 | ADRA2A (0.46) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL570524 | 0.76 | ADRA2A (0.47) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL28220351 | 0.74 | ADRA2A (0.46) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL28219788 | 0.74 | ADRA2A (0.46) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL6497003 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL28610444 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL22645117 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL3783184 | 0.73 | ADRA2A (0.41) | KDM4EALDH1A1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | KDM4E 1022/4885ALDH1A1 4320/4885ADRA2A 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.