Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327450 | 0.77 | ABL1 (0.31) | SMN1; SMN2ABL1BCR | |
| SCHEMBL24327019 | 0.74 | ALDH1A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL24328335 | 0.65 | HCRTR2 (0.35) | — | |
| SCHEMBL24327036 | 0.64 | CDK1 (0.39) | — | |
| SCHEMBL21937662 | 0.64 | NUAK1 (0.36) | SMN1; SMN2 | |
| SCHEMBL1491746 | 0.60 | SMN1; SMN2 (0.71) | SMN1; SMN2ABL1BCR | |
| SCHEMBL29651265 | 0.60 | NPC1 (0.53) | SMN1; SMN2 | |
| SCHEMBL25499920 | 0.60 | NPC1 (0.53) | SMN1; SMN2 | |
| SCHEMBL24328340 | 0.60 | ALK (0.38) | — | |
| SCHEMBL24328599 | 0.60 | RPS6KB1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063106-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BEIGENE, LTD. (KY) | 2022-03-31 | — | — | WO | disclosed |