Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328354 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL24328903 | 0.85 | KDM4E (0.47) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL24328359 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL28409196 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL24328919 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| Hyrtioerectine C SCHEMBL6714773 | 0.81 | HTR2C (0.72) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL28891541 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL30024734 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL30023635 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTBLMNPSR1 | |
| SCHEMBL24328920 | 0.80 | TSHR (0.65) | SMN1; SMN2KDM4EMAPTBLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | SMN1; SMN2 3812/4885KDM4E 1022/4885MAPT 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.