Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327424 | 0.77 | MTOR (0.48) | MEN1KMT2APOLBGAASMN1; SMN2 | |
| SCHEMBL11142389 | 0.70 | ALDH1A1 (0.71) | CYP1A2MEN1KMT2APOLBGAA | |
| SCHEMBL24328063 | 0.69 | NPC1 (0.52) | CYP1A2CYP3A4MEN1KMT2APOLB | |
| SCHEMBL27477545 | 0.67 | CYP1A2 (0.43) | CYP1A2CYP3A4MEN1KMT2APOLB | |
| SCHEMBL5523767 | 0.65 | CYP1A2 (0.58) | CYP1A2CYP3A4MEN1KMT2AGAA | |
| SCHEMBL24327926 | 0.64 | CYP1A2 (0.40) | CYP1A2CYP3A4MEN1KMT2AGAA | |
| SCHEMBL24327446 | 0.64 | MTOR (0.48) | CA1CA2CA9LMNAMAPT | |
| SCHEMBL29140936 | 0.64 | MTOR (0.78) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL11682405 | 0.64 | HSP90AA1 (0.43) | POLBSMN1; SMN2NPC1RAB9AHDAC6 | |
| SCHEMBL12585097 | 0.64 | MEN1 (0.79) | MEN1KMT2APOLBGAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |