Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 2/20 | 0.42 |
| ▸ | GIPR | P48546 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327446 | 0.89 | MTOR (0.48) | MTORGCGRGIPRLMNAMAPT | |
| SCHEMBL24328772 | 0.87 | MTOR (0.58) | MTORNPC1LMNARAB9AALDH1A1 | |
| SCHEMBL24327422 | 0.83 | TP53 (0.56) | MTORLMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24327551 | 0.81 | MTOR (0.68) | MTORNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24327548 | 0.80 | MTOR (0.53) | MTORLMNAALDH1A1 | |
| SCHEMBL24328826 | 0.77 | CYP1A2 (0.41) | NPC1LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL24327550 | 0.76 | DCUN1D1 (0.60) | LMNARAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL24328063 | 0.73 | NPC1 (0.52) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24327968 | 0.68 | ALDH1A1 (0.65) | MTORNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31356653 | 0.67 | MAPT (0.57) | LMNAALDH1A1MAPTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |