Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.43 |
| ▸ | GIPR | P48546 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327548 | 0.91 | MTOR (0.53) | MTORP2RX1LMNANFKB1NFKB2 | |
| SCHEMBL24328772 | 0.91 | MTOR (0.58) | MTORMAPTLMNAKIF11CA12 | |
| SCHEMBL24327422 | 0.89 | TP53 (0.56) | MTORMAPTLMNAKIF11 | |
| SCHEMBL24327424 | 0.89 | MTOR (0.48) | MTORGCGRGIPRMAPTLMNA | |
| SCHEMBL24327551 | 0.84 | MTOR (0.68) | MTORMAPTKIF11 | |
| SCHEMBL24327550 | 0.81 | DCUN1D1 (0.60) | MAPTLMNA | |
| SCHEMBL6816263 | 0.76 | GCGR (0.43) | MTORP2RX1GCGRGIPRMAPT | |
| SCHEMBL3299626 | 0.72 | MTOR (0.55) | MTORP2RX1LMNATACR1 | |
| SCHEMBL24327968 | 0.71 | ALDH1A1 (0.65) | MTORMAPTCA12CA1CA2 | |
| SCHEMBL27494437 | 0.71 | LMNA (0.46) | MTORP2RX1MAPTLMNAACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |