Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040505 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| SCHEMBL24327755 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| SCHEMBL15743150 | 0.87 | CYP3A4 (0.44) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| SCHEMBL11710727 | 0.84 | TSHR (0.44) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| SCHEMBL11713277 | 0.84 | KMT2A (0.47) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL11713887 | 0.83 | CYP3A4 (0.46) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| SCHEMBL27503970 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| SCHEMBL11716870 | 0.81 | TSHR (0.44) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| SCHEMBL11063759 | 0.81 | KDM4E (0.44) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E | |
| Maleic Acid SCHEMBL11714632 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | ALDH1A1 4320/4885CYP1A2 4385/4885TSHR 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.