Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FGB | P02675 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327741 | 1.00 | KDM4E (0.46) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| SCHEMBL1491038 | 0.77 | KDM4E (0.50) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| Bromide SCHEMBL28228586 | 0.75 | KDM4E (0.49) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| SCHEMBL25661045 | 0.75 | KDM4E (0.49) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28360520 | 0.75 | SMN1; SMN2 (0.49) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| SCHEMBL25660382 | 0.75 | KDM4E (0.49) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| Lactic Acid SCHEMBL27753588 | 0.74 | KDM4E (0.51) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| SCHEMBL27713110 | 0.73 | KDM4E (0.41) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL16700796 | 0.73 | KMT2A (0.49) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 | |
| Alanine SCHEMBL29260750 | 0.72 | KDM4E (0.46) | KDM4EKMT2ACYP2D6L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | KDM4E 1022/4885KMT2A 907/4885CYP2D6 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.