Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | QDPR | P09417 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15141399 | 0.83 | DRD2 (0.41) | DRD2DRD4HTR1AKCNH2CNR2 | |
| SCHEMBL21016389 | 0.83 | HTR1A (0.39) | DRD2HTR1ACNR2 | |
| SCHEMBL25121145 | 0.83 | HTR3E (0.51) | USP7QDPRDRD2DRD4HTR1A | |
| SCHEMBL17888476 | 0.81 | DRD2 (0.53) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL23865578 | 0.79 | HTR1A (0.48) | USP7QDPRDRD2DRD4HTR1A | |
| SCHEMBL25121130 | 0.79 | USP7 (0.41) | USP7QDPRDRD2DRD4HTR1A | |
| SCHEMBL29645408 | 0.79 | HTR1A (0.48) | USP7QDPRDRD2DRD4HTR1A | |
| SCHEMBL5338979 | 0.79 | HTR1A (0.48) | USP7QDPRDRD2DRD4HTR1A | |
| SCHEMBL29556164 | 0.79 | CNR2 (0.41) | DRD2DRD4HTR1AKCNH2CNR2 | |
| SCHEMBL15140526 | 0.79 | CNR2 (0.41) | DRD2DRD4HTR1AKCNH2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |